Doctor Strange in the Multiverse of Madness continues to soar at the box office, recently passing $500 million at the global box office as the superhero film heads into its second weekend. The sequel has made $222.75 million in the US and $309.8 million from international markets for a total global result of $532.5 million so far. The movie is not expected to be able to match its first-weekend performance this coming weekend, but the film’s solid B+ CinemaScore rating suggests word-of-mouth is trending in the right direction to help second-weekend numbers stay strong. In the Multiverse of Madness blasted off to $185 million US and $450 million for its worldwide total after its first weekend. For comparison, 2016’s original Doctor Strange made $85 million in the US for its opening weekend, ending its run with $232 million domestically and $677 million worldwide. The sequel reportedly had a mighty budget of $200 million to produce, and that does not count what are surely very sizable marketing and promotion costs. Every Upcoming Marvel Movie And TV Show, From Both The MCU And Sony See More After just one weekend, Doctor Strange in the Multiverse of Madness is already 2022’s third-biggest movie…