Jose Mourinho will inevitably be the centre of attention as he takes charge of Tottenham for the first time this weekend while Manchester City look to get their Premier League title challenge back on track against Chelsea. The former Chelsea and Manchester United manager has been charged with rescuing Spurs’ season after this week’s sacking of Mauricio Pochettino, with the club desperate to claw their way back into the top four.At the top of the table, runaway leaders Liverpool have a winnable-looking fixture away to Crystal Palace but the chasing pack cannot afford to allow the gap to widen further.City, licking their wounds after their 3-1 defeat by Liverpool earlier this month, host Frank Lampard’s Chelsea, who are one point above them in the table, eight points behind Jurgen Klopp’s side.Close Leicester, in second place, ahead of Chelsea on goal difference, travel to England’s south coast to take on Brighton. related news EPL: We are the champions and we want to defend’ says Guardiola ahead of Chelsea clash EPL: Liverpool urged to keep Premier League focus as fixture pile-up looms EPL: Arsenal manager Unai Emery under fire as Saints come to Emirates AFP Sport picks out some of the talking…